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Marla J Keller Selected Research

Anti-Infective Agents (Microbicides)

11/2016In vitro inhibition of human papillomavirus following use of a carrageenan-containing vaginal gel.
3/2011Female genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections.
8/2009Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety.
3/2009Understanding basic mechanisms and optimizing assays to evaluate the efficacy of vaginal microbicides.
1/2009Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety.
7/2008Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model.
7/2007Molecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infections.
5/2007A comprehensive murine model to evaluate topical vaginal microbicides: mucosal inflammation and susceptibility to genital herpes as surrogate markers of safety.
2/2007PRO 2000 elicits a decline in genital tract immune mediators without compromising intrinsic antimicrobial activity.
11/2006Impact of microbicides and sexually transmitted infections on mucosal immunity in the female genital tract.
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Marla J Keller Research Topics

Disease

13Infections
11/2016 - 06/2004
6Sexually Transmitted Diseases (Sexually Transmitted Disease)
10/2012 - 06/2004
6Herpes Genitalis (Genital Herpes)
01/2009 - 04/2005
4COVID-19
01/2022 - 08/2020
3Inflammation (Inflammations)
01/2019 - 05/2007
3Herpes Simplex
02/2010 - 01/2006
1Bacterial Vaginosis
12/2021
1Abdominal Pain (Pain, Abdominal)
01/2019
1Ulcer
01/2019
1Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
01/2019
1Acute Cholecystitis
01/2019
1Nausea
01/2019
1Coinfection
01/2017
1Malaria
09/2014
1Falciparum Malaria (Plasmodium falciparum Malaria)
09/2014
1Squamous Intraepithelial Lesions
07/2012
1Neoplasms (Cancer)
07/2012
1Uterine Cervical Dysplasia
07/2012
1Peripheral Arterial Disease
03/2010
1Acute Coronary Syndrome
03/2010
1Cardiovascular Diseases (Cardiovascular Disease)
03/2010
1HIV Infections (HIV Infection)
08/2009
1Herpesviridae Infections (Herpesvirus Infection)
07/2008
1Virus Diseases (Viral Diseases)
07/2007
1Acquired Immunodeficiency Syndrome (AIDS)
01/2005

Drug/Important Bio-Agent (IBA)

12Anti-Infective Agents (Microbicides)IBA
11/2016 - 02/2006
5PRO 2000 (PRO-2000)IBA
08/2009 - 06/2004
4Local Anti-Infective Agents (Antiseptics)IBA
07/2007 - 06/2004
3Pharmaceutical PreparationsIBA
01/2019 - 07/2007
3Tenofovir (Viread)FDA Link
01/2019 - 01/2009
3Biomarkers (Surrogate Marker)IBA
03/2009 - 05/2007
2Oxygen (Dioxygen)IBA
01/2022 - 10/2021
2Proteins (Proteins, Gene)FDA Link
12/2021 - 01/2009
2Contraceptive Agents (Contraceptives)IBA
02/2010 - 03/2009
2cellulose sulfateIBA
08/2009 - 06/2004
2Nonoxynol (Nonoxynol 9)FDA Link
08/2009 - 01/2009
2Reverse Transcriptase InhibitorsIBA
07/2008 - 07/2007
1boldenone undecylenate (Equipoise)IBA
01/2022
1Metronidazole (Metric)FDA LinkGeneric
12/2021
1Neutralizing AntibodiesIBA
10/2020
1CytokinesIBA
10/2020
1GlucocorticoidsIBA
08/2020
1InterleukinsIBA
01/2017
1CarrageenanIBA
11/2016
1LubricantsIBA
11/2016
1Lumefantrine Drug Combination Artemether (Coartem)FDA Link
09/2014
1Aligeron (AS 2)IBA
07/2012
1Cytokine Receptors (Cytokine Receptor)IBA
03/2010
1OsteoprotegerinIBA
03/2010
1Hormones (Hormone)IBA
02/2010
1LuciferasesIBA
01/2010
1AdenineFDA LinkGeneric
08/2009
1hydroxyethylcelluloseIBA
01/2009
1GelsIBA
07/2008
1PolymersIBA
01/2007
1DNA (Deoxyribonucleic Acid)IBA
01/2007
1DefensinsIBA
12/2006
1beta-DefensinsIBA
12/2006
1alpha-DefensinsIBA
12/2006
1Antimicrobial PeptidesIBA
01/2005
1Complement System Proteins (Complement)IBA
01/2005
1Acyclovir (Aciclovir)FDA LinkGeneric
06/2004
1polystyrene sulfonic acid (sodium polystyrene sulfonate)FDA LinkGeneric
06/2004

Therapy/Procedure

2Therapeutics
01/2019 - 01/2007
1Artificial Respiration (Mechanical Ventilation)
08/2020
1Transplantation
01/2019
1Condoms (Condom)
10/2012
1Hormonal Contraception
02/2010